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The main asymmetric overall synthesis of conolidine was designed by Micalizio and coworkers in 2011.[two] Thi
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While this research identifies the correlation between conolidine and ACKR3, the mechanism of action s
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2.2]decane Main and defining the geometry of the exocyclic double bond. The activation energies of formation of your vinyl-gold intermediates were being calculated and revealed a silyl enol ether with an unprotected indole moiety as an appropriate precursor for your Toste cyclization. This six-m
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